![]() This drug should not be taken along with certain medications, including other antidepressants or sleeping pills. Tell your doctor right away if, while taking mirtazapine, you develop chest pain, a rapid heartbeat, seizures, or flu-like symptoms such as a fever or sore throat. Some of the most common include: 12Ĭertain serious side effects are a cause for concern. Mirtazapine use is associated with several side effects. ![]() 4 Always follow your doctor’s instructions when it comes to starting or changing a drug regimen. The drug may have stronger effects in elderly adults or in people with kidney or liver problems, so these groups of people may be given a smaller starting dose. Some people may need lower mirtazapine doses. If this dosage isn’t helping treat your symptoms, your doctor may recommend slowly and gradually increasing your dose. 10 Mirtazapine Recommended Dosageĭoctors most often recommend taking 15 mg of mirtazapine to start with. Although mirtazapine works well to induce sleep temporarily, it is often much less effective over the long term. Much like other sleeping medications, the body quickly adapts to this drug. Unfortunately, the effects of mirtazapine are often short-lived. The end result is that they tend to get higher-quality, more rejuvenating rest. They also spend more time in deeper sleep stages. People who take mirtazapine take longer to reach REM sleep. In this way, depression has a negative effect on overall sleep quality. They also spend less time in slow-wave sleep - the deepest sleep stage, during which the body spends the most time healing and rebuilding tissues. Studies show that people with depression reach REM stage more quickly and spend more time in this sleep stage throughout the night. 8ĭepression can impact these sleep phases. You need to spend a certain amount of time in both phases to feel fully rested. Sleep is broadly divided into two phases: rapid eye movement (REM) sleep and non-rapid eye movement (NREM) sleep. To understand how mirtazapine can help, it is useful to grasp the impact of depression on sleep. Those who took the drug had higher-quality sleep and spent more time asleep while at night. 6Īdditionally, in a review of 15 studies of people with major depressive disorder, researchers determined that mirtazapine could improve insomnia symptoms. Six people dropped out of the study due to side effects, but the remaining study participants saw their insomnia symptoms improve or disappear. In a 2018 study, researchers gave mirtazapine to 28 men with depression, suicidal thoughts, and insomnia. Research has found that mirtazapine may help treat insomnia. 3 People who take this drug may soon start to feel tired. Sleepiness is one of the most common side effects of mirtazapine. These neurotransmitters help control mood, stress levels, and sleep/wake cycles. In particular, it boosts the effects of serotonin and noradrenaline. Mirtazapine increases levels of chemical messengers called neurotransmitters in the brain. 3 Doctors may also choose to prescribe mirtazapine “off-label” to help with various types of anxiety disorders, obsessive-compulsive disorder, and insomnia. Food and Drug Administration (FDA) to treat major depressive disorder. Mirtazapine, which also goes by the brand name Remeron, is a type of tetracyclic antidepressant. Some people find that these drugs can act as a quick fix for insomnia, while others have had better luck with other treatments. These medications can change brain chemistry to strengthen processes that lead to sleep. Some prescription sleep medications, including mirtazapine, are antidepressants. 1 Additionally, one out of three older adults turns to prescription drugs for better rest. Studies show that more than nine million adults in the U.S.
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